This exploratory research project focuses on the role of economic incentives in industrial symbiosis, a model of circular economy, and the utilization of industrial waste in Sub-Saharan Africa. Industrial symbiosis is a type of B2B-synergy whereby one actor uses the waste or by-products of another actor as a production input. The main objective of the research project is to contribute to the understanding of the productivity and environmental pressures in Sub-Saharan Africa and to analyse possible solutions for cleaner production. It operates with two research questions on (1) the economic factors of industrial symbiosis locally and (2) the compatibility of potential incentives’ implementation with the current local regulations. Qualitative and quantitative data collected in Ghana, Mauritius and Uganda will be analysed through company and industrial park mini case studies and the comparison of the three countries’ relevant regulatory and policy frameworks. The final research outputs will be policy recommendations and further research directions.